We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Read More
9
Vitamin C helps rheumatoid arthritis
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance.
We explored how vitamin C supplementation might affect rheumatoid arthritis (RA), an autoimmune disorder that causes chronic inflammation. Our research focused on whether vitamin C could help restore balance in gut microbiota, which previous findings indicated could worsen RA by breaking down vitamin C.
Using collagen-induced arthritis (CIA) mouse models, we conducted a series of tests, including biochemical and microbiological evaluations. The outcome was promising: vitamin C not only helped rebalance the gut microbiota but also reduced inflammation typical of RA, as seen in the notable decrease in pro-inflammatory cytokines like IL-6 and TNF-α.
In essence, the treatment with vitamin C showed significant benefits in alleviating RA symptoms in our study. These findings suggest that vitamin C could be a useful therapeutic option for managing rheumatoid arthritis effectively by targeting gut health.
Read More
9
Zinc supplementation benefits MS models
Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.
We explored how dietary zinc levels influence spinal cord damage and gene expressions associated with Multiple Sclerosis (MS) using a cuprizone-induced rat model. The study included 46 adult male Wistar rats divided into five groups, with some receiving zinc supplementation while others followed a zinc-deficient diet.
After eight weeks of treatment, we found that the rats with MS symptoms showed elevated markers of tissue damage and inflammation, particularly in the groups that lacked zinc. Notably, those receiving zinc supplementation exhibited significantly reduced levels of harmful substances, bringing them back closer to control levels.
Our findings highlight zinc's protective effects in a model of MS, suggesting that incorporating zinc into treatment plans could help alleviate some symptoms associated with this autoimmune disorder. This is promising for future treatment strategies for those affected by MS.
Read More
Most Useful Reviews
9
Great for throat
4 people found this helpful
These pleasant throat lozenges have a slightly sour berry taste and are highly effective against sore throats and ARVI symptoms. My husband finds them especially beneficial. We take them alongside a throat spray, and the results are fantastic!
Read More
9
Strong immunity booster
1 people found this helpful
These lozenges truly work! I wasn't expecting such impressive results. I suggest everyone keep these in their first aid kit. They helped me avoid illness from a sore throat and runny nose in just three days. I give them to my children as well to boost their immunity.
Read More
9
Prevents cold onset
1 people found this helpful
After reading the reviews, I ordered two jars without regret! We don't take it regularly as we have our multivitamins, but when a cold approaches, I reach for this miracle jar, and the illness either lessens or passes quickly. I will certainly order more.
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
Read More
9
Vitamin C aids rheumatoid arthritis treatment
A bioactive and biodegradable vitamin C stearate-based injectable hydrogel alleviates experimental inflammatory arthritis.
This study investigated the effects of a specially formulated hydrogel that combines vitamin C with 9-aminoacridine (9AA) on a model of rheumatoid arthritis (RA). We saw that this hydrogel is not only bioactive but also biodegradable, making it a potential candidate for treating this chronic autoimmune condition.
Our research showed that the combination of vitamin C—specifically in the form of 6-stearoyl-L-ascorbic acid—and 9AA could significantly reduce inflammation in our experimental model. By acting on specific pathways, such as the NR4A1 nuclear receptor, the hydrogel appears to exert anti-inflammatory effects that could alleviate some symptoms of arthritis.
We also noted that vitamin C plays a dual role by promoting collagen production, which is essential for joint health. This is crucial since RA leads to the deterioration of joint tissues.
In conclusion, our findings suggest that using this hydrogel could represent a more effective treatment strategy for RA compared to existing options. With its ability to reduce inflammation and promote tissue healing, this innovative approach offers hope to those suffering from this debilitating condition.
Read More
9
Vitamin C helps rheumatoid arthritis
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance.
We explored how vitamin C supplementation might affect rheumatoid arthritis (RA), an autoimmune disorder that causes chronic inflammation. Our research focused on whether vitamin C could help restore balance in gut microbiota, which previous findings indicated could worsen RA by breaking down vitamin C.
Using collagen-induced arthritis (CIA) mouse models, we conducted a series of tests, including biochemical and microbiological evaluations. The outcome was promising: vitamin C not only helped rebalance the gut microbiota but also reduced inflammation typical of RA, as seen in the notable decrease in pro-inflammatory cytokines like IL-6 and TNF-α.
In essence, the treatment with vitamin C showed significant benefits in alleviating RA symptoms in our study. These findings suggest that vitamin C could be a useful therapeutic option for managing rheumatoid arthritis effectively by targeting gut health.
Read More
9
Ascorbyl palmitate targets inflammation
Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome.
We examined the effects of ascorbyl palmitate (AP), a derivative of vitamin C, on the NLRP3 inflammasome, which plays a significant role in various autoimmune disorders. The research shows that AP effectively inhibits the activation of this inflammasome, suggesting it could be a powerful tool in managing inflammation-driven diseases.
Notably, AP showed greater potency and specificity in inhibiting the inflammasome compared to regular vitamin C. It appears to achieve this by scavenging harmful reactive oxygen species and disrupting key interactions necessary for inflammasome assembly.
Furthermore, we found that AP exhibited more pronounced protective effects in models of systemic inflammation and conditions like colitis and autoimmune encephalomyelitis than standard vitamin C treatments. This strengthens the case that AP could be a viable therapeutic option for combating NLRP3-driven diseases, presenting an exciting avenue for further research and potential clinical applications.
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9
Vitamin C's Role in Inflammation
Rheumatologic manifestations with elevated levels of IL-6, IL-17A, and IL-23 in a patient with scurvy.
We observed a fascinating case involving an 11-year-old boy suffering from symptoms of scurvy, a condition arising from severe vitamin C deficiency. This boy had multiple issues, including iron-deficiency anemia, symptoms resembling bone infections, and muscle inflammation, particularly in his legs. His selective diet, likely due to a mild developmental disorder, led to a significant deficiency in vitamin C.
After he was diagnosed, we administered intravenous and oral vitamin C, which remarkably eased his joint and muscle pain within just a week. Following four months of supplementation, he showed complete recovery with no lingering symptoms or abnormal lab findings.
Notably, we found high levels of certain pro-inflammatory markers, specifically interleukin-6, IL-17A, and IL-23, likely linked to an immune response involving T-helper 17 cells. This association presents an intriguing insight into the inflammatory processes that might be involved in scurvy and, potentially, in other autoimmune disorders.
Our observations hint that vitamin C might play a pivotal role in addressing inflammation linked to autoimmune conditions, paving the way for enhanced understanding and treatment options in the future.
These pleasant throat lozenges have a slightly sour berry taste and are highly effective against sore throats and ARVI symptoms. My husband finds them especially beneficial. We take them alongside a throat spray, and the results are fantastic!
Read More
9
Strong immunity booster
1 people found this helpful
These lozenges truly work! I wasn't expecting such impressive results. I suggest everyone keep these in their first aid kit. They helped me avoid illness from a sore throat and runny nose in just three days. I give them to my children as well to boost their immunity.
Read More
9
Prevents cold onset
1 people found this helpful
After reading the reviews, I ordered two jars without regret! We don't take it regularly as we have our multivitamins, but when a cold approaches, I reach for this miracle jar, and the illness either lessens or passes quickly. I will certainly order more.
Read More
9
Family favourite
1 people found this helpful
I’m pleased with this elderberry remedy. I ordered it for my whole family. My daughter was the first to fall ill, and at the first symptoms, I gave her a Sambucus tablet in the evening. It has a pleasant, slightly sour taste, and she felt better by morning and was ready for school. She took another tablet for prevention for a week. It's an effective supplement, highly recommended!
Read More
7.5
Autumn-winter support
1 people found this helpful
These vitamins are excellent! I take them to strengthen my immunity during the autumn-winter months. The combination of zinc, vitamin C, and elderberry helps me recover faster or even avoid illness altogether. They have a pleasant, slightly sour taste, and I plan to order more.
An autoimmune disorder occurs when the body's immune system mistakenly attacks its own healthy cells and tissues, believing them to be foreign invaders, such as bacteria or viruses. This reaction can lead to inflammation, tissue damage, and impaired function of the affected organs. There are over 80 known autoimmune diseases, including rheumatoid arthritis, lupus, multiple sclerosis, and type 1 diabetes, each with its own specific symptoms and treatment options. The exact cause of these disorders is still unclear, but a combination of genetic, environmental, and hormonal factors is believed to play a role in their development.
Diagnosis of autoimmune disorders often involves a combination of physical examinations, assessment of symptoms, blood tests, and imaging studies to evaluate organ involvement. Treatment typically focuses on managing symptoms and controlling the immune response using medications such as corticosteroids, immunosuppressants, and biologics. In addition to medication, lifestyle modifications, such as stress management and a balanced diet, can be beneficial in managing symptoms. If you suspect you have an autoimmune condition, it's important to consult a healthcare professional for proper evaluation and tailored treatment options.
Elderberry (Sambucus) refers to a genus of flowering plants in the family Adoxaceae, comprising several species known for their small berries and traditional medicinal uses. The most commonly recognized species is the European elder, Sambucus nigra, which has been utilized in folk medicine for centuries due to its rich nutrient profile, including antioxidants, vitamins A and C, and dietary fiber. Elderberries are typically fragrant clusters of small, dark purple to black berries that are used in a variety of culinary applications, such as jams, syrups, and wine.
In recent years, elderberry has gained popularity for its potential health benefits, particularly for supporting immune health. Many people consume elderberry supplements or syrups to help alleviate symptoms of colds and flu, with some studies suggesting they may reduce the duration and severity of viral infections. However, it’s important to note that raw elderberries, as well as other parts of the elderberry plant, can be toxic if consumed in large amounts. Therefore, it's recommended to use elderberry products that are properly processed and prepared to ensure safety and efficacy.
While some studies suggest that elderberry (Sambucus) may have immune-boosting properties due to its high levels of antioxidants, research specifically linking elderberry to the treatment or management of autoimmune disorders is limited. Autoimmune disorders, where the body's immune system mistakenly attacks healthy cells, are complex conditions that often require comprehensive management strategies tailored to the individual. Though elderberry may support overall health, particularly in bolstering the immune system, it's essential to approach these claims with caution.
If you are considering using elderberry as a supplement for an autoimmune disorder, it is crucial to consult with a healthcare provider. They can provide personalized advice based on your health status and other treatments you may be receiving. While elderberry may offer some benefits as part of a healthy lifestyle, relying on it exclusively without medical guidance could potentially interfere with prescribed therapies or conditions. Always prioritize a holistic approach and expert input when dealing with autoimmune disorders.
Users report varying timelines for noticing results from taking supplements aimed at autoimmune disorders, particularly those containing ingredients like zinc, vitamin C, and elderberry. Many individuals experienced improvements within a few days, with one user sharing that after taking a remedy at the onset of illness, they felt better by the next day (Read Review). This sentiment is echoed by others who indicated noticeable effects in as little as three days (Read Review).
However, there are also accounts that emphasize the importance of consistent use over a longer period, with some users noting significant benefits after a month or more, especially in the context of boosting immune response during colder months (Read Review). Thus, while immediate results can be encouraging, others suggest a longer commitment to the supplement may be necessary for optimal benefits, particularly for chronic conditions like autoimmune disorders.
Recent scientific research supports the use of vitamin C in managing various autoimmune disorders, including rheumatoid arthritis and Hashimoto's disease. A study on the effectiveness of vitamin C combined with inorganic nitrates showed promising results in reducing symptoms like joint swelling and improving overall joint health in an animal model of rheumatoid arthritis [1]. Furthermore, a separate analysis revealed a significant negative correlation between vitamin C intake and the likelihood of developing hypothyroidism in individuals with Hashimoto's thyroiditis, suggesting that higher vitamin C levels may offer protective benefits against this condition [2].
Vitamin C's potential benefits extend further into broader autoimmune management. Research indicates that vitamin C supplementation can modulate immune responses, reduce inflammation, and inhibit harmful autoantibody production, all of which are crucial for autoimmune regulation [3]. Notably, in a model of collagen-induced arthritis, vitamin C was shown to delay disease onset and lessen severity, emphasizing its role in alleviating autoimmune conditions [3]. However, while these findings are promising, more extensive human studies are necessary to establish definitive recommendations regarding vitamin C supplementation for specific autoimmune disorders.
Based on user reviews, many individuals highlight significant improvements in their symptoms after using supplements combining zinc, vitamin C, and elderberry. Users report feeling relief from sore throats and other flu-like symptoms within a remarkably short timeframe—a common theme is improvement within just a few days. For instance, one user noted that they avoided illness after taking lozenges for three days during the onset of a sore throat and runny nose (Read Review). Another review emphasizes that a child felt better overnight after beginning treatment with an elderberry tablet, allowing them to confidently return to school the following day (Read Review).
Additionally, some users indicated that a consistent approach, such as taking the supplements at the first sign of illness or as a daily preventative measure, resulted in even greater symptom relief. For instance, families reported that their children became ill less frequently once seizing on the preventive benefits of these remedies (Read Review). The general consensus is that while individual results can vary, many users have found these lozenges and supplements to be effective in reducing the duration and severity of cold symptoms.
Users report positive experiences when combining this supplement with other remedies like throat sprays, suggesting a synergistic effect that enhances recovery from sore throats and cold symptoms. One reviewer mentioned that taking throat lozenges alongside a throat spray yielded fantastic results in alleviating their symptoms (Read Review). Another user noted that they began taking additional vitamin C at 1000 mg concurrently with the elderberry and zinc lozenges, leading to faster recovery from cold symptoms (Read Review).
These anecdotal reports highlight that many individuals found success in using the elderberry, vitamin C, and zinc combination not just alone but enhanced by additional supplements for better immunity support. One user explicitly stated that boosting their regimen allowed them to manage the virus with greater ease, underscoring the potential benefits of a comprehensive approach that includes various supportive supplements (Read Review). Overall, the consensus among users indicates a favorable outcome when these supplements are used together, especially during cold and flu seasons.
Based on user reviews, it appears that determining the right dose of Elderberry Sambucus is essential, especially for those managing an autoimmune disorder or similar health challenges. Users commonly report taking one lozenge daily as a preventive measure during the cold season, particularly for children. For instance, one user noted that her daughter benefited significantly from taking one lozenge each morning, while also stating that doubling the dose to two lozenges when symptoms arise contributed to quicker recovery Read Review.
Moreover, others echoed the sentiment, highlighting the importance of early intervention with higher doses at the onset of illness. Several users mentioned using the lozenges effectively when they felt the first signs of a cold, with increased doses reportedly leading to swifter recovery Read Review. Overall, it seems that users generally find success with a flexible dosing strategy, adjusting their intake based on illness prevention and symptom management.
9
Family favourite
1 people found this helpful
I’m pleased with this elderberry remedy. I ordered it for my whole family. My daughter was the first to fall ill, and at the first symptoms, I gave her a Sambucus tablet in the evening. It has a pleasant, slightly sour taste, and she felt better by morning and was ready for school. She took another tablet for prevention for a week. It's an effective supplement, highly recommended!
9
Strong immunity booster
1 people found this helpful
These lozenges truly work! I wasn't expecting such impressive results. I suggest everyone keep these in their first aid kit. They helped me avoid illness from a sore throat and runny nose in just three days. I give them to my children as well to boost their immunity.
9
Prevents severe colds
2 people found this helpful
This medication should be taken at the beginning of the cold season to strengthen the immune system. I have purchased it for my daughter second time; previously, after taking it for 1.5 months, she didn’t suffer from a severe cold, only a mild runny nose.
7.5
Less frequent illness
2 people found this helpful
I really like this combination of ingredients; it's a powerful supplement for strengthening the immune system. After giving it to my children, I noticed they became ill less often. I regularly order this quality product from NOW Foods and appreciate the use of natural ingredients.
9
Great for throat
4 people found this helpful
These pleasant throat lozenges have a slightly sour berry taste and are highly effective against sore throats and ARVI symptoms. My husband finds them especially beneficial. We take them alongside a throat spray, and the results are fantastic!
7.5
Rapid recovery noted
Wonderful! This is truly miraculous! At the first signs of a cold, I commence taking additional vitamin C at 1000 mg and find I recover more swiftly. By adding elderberry, I also manage the virus with greater ease, and coupled with extra vitamin C, the results appear quickly. I've also ordered vitamin C from iHerb. Please give a thumbs up 👍. It costs you nothing, but it brings me joy. Wishing you all good health!!!
9
Great for children’s immunity
1 people found this helpful
As a mother, I worry about my child's health. My daughter has had weak immunity since birth, often missing school due to illness. We've tried elderberry syrup before, which worked well, but I find these lozenges to be the best option. To maintain immunity during the cold season, just one lozenge each morning is needed, and if she does get sick, taking two helps her recover quickly. We're in our second season of using this drug, and I'm very pleased with the results!
6
Effective prevention
1 people found this helpful
This is not my first order of elderberry and zinc! I give my child one tablet after breakfast before school for ARVI prevention. When a runny nose begins, I increase it to two tablets a day and notice that recovery happens more swiftly. Highly recommend for other parents!
8
Vitamin C aids in arthritis prevention
Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis.
We examined the effects of vitamin C when combined with inorganic nitrates on rheumatoid arthritis (RA) in collagen-induced arthritis (CIA) rats. The results revealed that this combination not only reduced foot swelling and arthritis scores but also showed promising improvements in joint health by reducing synovial hyperplasia and bone loss.
While vitamin C alone is beneficial, it truly shines when paired with nitrates. This partnership appears to enhance the overall anti-inflammatory effects, as we noted a decrease in important inflammatory markers, including TNF-α and IL-1β, which are often elevated in autoimmune disorders.
The findings suggest that vitamin C helps in reducing inflammation by silencing pathways that contribute toRA symptoms. However, it’s essential to recognize that the study focused on the combination treatment, making it challenging to pinpoint vitamin C's standalone contributions.
Overall, our investigation offers valuable insights into how dietary components like vitamin C can play a significant role in developing strategies to prevent chronic inflammation associated with autoimmune conditions.
8
Vitamin C may lower hypothyroidism risk
Association between total vitamin C intake and hypothyroidism among Hashimoto thyroiditis: National Health and Nutrition Examination Survey, 2007-2012.
We aimed to understand how vitamin C intake influences hypothyroidism in patients with Hashimoto thyroiditis (HT). Through a detailed analysis of data collected in the National Health and Nutrition Examination Survey from 2007 to 2012, we found notable results that shed light on this relationship.
Our study involved looking at various participants categorized by their total vitamin C intake. We discovered a significant negative correlation between the amount of vitamin C consumed and the likelihood of developing hypothyroidism in those with HT. In essence, individuals drinking higher amounts of vitamin C—up to 1,258.9 mg per day—exhibited a lower probability of experiencing hypothyroidism compared to those with minimal intake.
Furthermore, this connection remained apparent even when we examined different age groups and genders, indicating that vitamin C could play a protective role against hypothyroidism related to Hashimoto's thyroiditis. Thus, our findings suggest that enhancing vitamin C consumption might be a beneficial strategy for those managing this autoimmune condition.
9
Vitamin C impacts autoimmune response
Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies.
We investigated how vitamin C, also known as ascorbic acid, might impact autoimmune disorders like rheumatoid arthritis. Through a study involving a mouse model of collagen-induced arthritis, we administered vitamin C or a placebo solution and observed the effects on the immune response and disease progression.
Notably, the research showed that mice given vitamin C experienced a significant delay in the onset of arthritis and a reduction in disease severity. This suggests that vitamin C can play a critical role in managing autoimmune conditions by minimizing the production of autoantibodies, which are harmful antibodies that mistakenly attack the body's tissues.
Our findings revealed that vitamin C reduced the number of plasma cells and decreased antibody production in response to immunization. This indicates that vitamin C influences the immune system's response at a cellular level, helping to prevent the emergence of autoreactive plasma cells. We also discovered that the mechanism behind this effect involved inhibiting the Stat3 signaling pathway, leading to less activation of autoreactive immune components.
Ultimately, these results highlight the potential of vitamin C not just as a nutrient, but as a strategic tool in managing autoimmune disorders. By simply supplementing with vitamin C, there may be a way to intervene positively in the progression of diseases like rheumatoid arthritis.
References
Zhang H, Zhang Y, Zhang Y, Wei H, Jin S, et al. Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis. Food Funct. 2025;16:673. doi:10.1039/d4fo03096f
Chen L, Mao Y, Chen G. Association between total vitamin C intake and hypothyroidism among Hashimoto thyroiditis: National Health and Nutrition Examination Survey, 2007-2012. Br J Nutr. 2024;132:1575. doi:10.1017/S0007114524001715
Yin Y, Wu S. Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies. Cell Commun Signal. 2024;22:373. doi:10.1186/s12964-024-01756-x
Isola S, Gammeri L, Furci F, Gangemi S, Pioggia G, et al. Vitamin C Supplementation in the Treatment of Autoimmune and Onco-Hematological Diseases: From Prophylaxis to Adjuvant Therapy. Int J Mol Sci. 2024;25. doi:10.3390/ijms25137284
Ali A, Jori C, Kumar A, Vyawahare A, Kumar J, et al. A bioactive and biodegradable vitamin C stearate-based injectable hydrogel alleviates experimental inflammatory arthritis. Biomater Sci. 2024;12:3389. doi:10.1039/d4bm00243a
Zhang Y, Zhen S, Xu H, Sun S, Wang Z, et al. Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance. Biosci Trends. 2024;18:187. doi:10.5582/bst.2024.01037
Zhang L, Li G, Lin B, He H, Zhou R, et al. Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome. Int Immunopharmacol. 2024;131:111915. doi:10.1016/j.intimp.2024.111915
Santiworakul C, Saisorn W, Siripen N, Leelahavanichkul A, Rianthavorn P. Interleukin-8 and neutrophil extracellular traps in children with lupus nephritis and vitamin C deficiency. Pediatr Nephrol. 2024;39:1135. doi:10.1007/s00467-023-06189-1
Mungan S, Guzel I, Demirdogen BC. Association between Expanded Disability Status Scale score and dietary antioxidant capacity in patients with multiple sclerosis. Braz J Med Biol Res. 2023;56:e12776. doi:10.1590/1414-431X2023e12776
Farasati Far B, Behnoush AH, Ghondaghsaz E, Habibi MA, Khalaji A. The interplay between vitamin C and thyroid. Endocrinol Diabetes Metab. 2023;6:e432. doi:10.1002/edm2.432
Ueki M, Sakamoto K, Nishioka N, Ohata H, Nobuta T, et al. Rheumatologic manifestations with elevated levels of IL-6, IL-17A, and IL-23 in a patient with scurvy. Mod Rheumatol Case Rep. 2023;7:302. doi:10.1093/mrcr/rxac059
Shao Y, Mu Q, Wang R, Luo H, Song Z, et al. SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease. Sci China Life Sci. 2025. doi:10.1007/s11427-024-2817-y
Chen L, Yan C, Huang C, Jiang Z, Lin R, et al. Higher dietary zinc intake increases the risk of autoimmune thyroiditis. Postgrad Med J. 2025. doi:10.1093/postmj/qgae202
Wu R, Li Y, Peng H, Yang Z, Wang Y, et al. Association Between Serum Trace Elements Level and Alopecia Areata: A Systematic Review and Meta-Analysis. J Cosmet Dermatol. 2025;24:e16740. doi:10.1111/jocd.16740
Bayiroglu AF, Acar G, Gulbahce-Mutlu E, Baltaci SB, Mogulkoc R, et al. Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model. J Trace Elem Med Biol. 2024;86:127540. doi:10.1016/j.jtemb.2024.127540
Fang D, Jiang D, Shi G, Song Y. The association between dietary zinc intake and osteopenia, osteoporosis in patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2024;25:710. doi:10.1186/s12891-024-07768-5
Cheng J, Rink L, Wessels I. Zinc Supplementation Reduces the Formation of Neutrophil Extracellular Traps by Decreasing the Expression of Peptidyl Arginine Deiminase 4. Mol Nutr Food Res. 2024;68:e2400013. doi:10.1002/mnfr.202400013
Faden DF, Stone CJ, Xie L, Lopes Almeida Gomes L, Werth VP. Prevalence and Risk of Immunostimulatory Herbal Supplement Treatment Among Autoimmune Dermatology Patients. ACR Open Rheumatol. 2024;6:820. doi:10.1002/acr2.11735